G. Eric Schaller

Academic Appointments

Professor of Biological Sciences
Professor in the Molecular and Cellular Biology Graduate Program
Fellow of the American Association for the Advancement of Science

We use biochemical, molecular, and genetic strategies to study how plants grow and respond to changes in their environment. Our research is focused on the roles played by the plant hormones ethylene and cytokinin, and is relevant to solving real-world agricultural problems, such as the control of ripening and senescence.

339 Life Sciences Center
HB 6044
Biological Sciences
B.S. Michigan State University
Ph.D. University of Wisconsin at Madison

Selected Publications

Hodgens, C., Chang, N., Schaller, G.E., Kieber, J,J. (2020) Mutagenomics: A Rapid, High-Throughput Method to Identify Causative Mutations from a Genetic Screen. Plant Physiology. Dec;184(4):1658-1673.

Yamburenko, M.V., Worthen, J.M., Zeenat, A., Azhar, B.J., Swain, S., Couitt, A.R., Shakeel, S.N., Kieber, J.J., Schaller, G.E. Functional Analysis of the Rice Type-B Response Regulator RR22. (2020) Frontiers of Plant Science. 0;11:577676.

Burr, C.A., Sun, J., Yamburenko, M.V. Willoughby, A., Hodgens, C., Boeshore, S.L., Elmore, A., Atkinson, J., Nimchuk, Z.L., Bishopp, A.,Schaller, G.E., Kieber, J.J. (2020) The HK5 and HK6 cytokinin receptors mediate diverse developmental pathways in rice. Development. Oct 27;147(20):dev191734

Zubo, Y.O., Schaller, G.E. (2020) Role of the Cytokinin-Activated Type-B Response Regulators in Hormone CrosstalkPlants (Basel). Jan 30;9(2):166.

Worthen, J.M., Yamburenko, M.V., Lim, J., Nimchuk, Z.L., Kieber, J.J., Schaller, G.E. (2019) Type-B response regulators of rice play key roles in growth, development and cytokinin signaling. Development. Jul 10;146(13):dev174870.

Binder, B.M., Kim, H.J., Mathews, D.E., Hutchison, C.E., Kieber, J.J., Schaller, G.E. (2018) A role for two-component signaling elements in the Arabidopsis growth recovery response to ethylene. Plant Direct. May 9;2(5):e00058

Potter, K.C., Wang, J., Schaller, G.E., Kieber, J.J. (2018) Cytokinin modulates context-dependent chromatin accessibility through the type-B response regulators. Nature Plants. Dec;4(12):1102-1111.

Zubo, Y.O., Blakley, I.C., Franco-Zorrilla, J.M., Yamburenko, M.V., Solano, R., Kieber, J.J., Loraine, A.E., and Schaller, G.E. (2018) Coordination of chloroplast development through the action of the GNC and GLK transcription factor families. Plant Physiol. 178:130-147. 

Kieber, J.J., and Schaller, G.E. (2018) Cytokinin signaling in plant development. Development. 145:dev149344  

Zubo, Y.O., Blakley, I.C., Yamburenko, M.V., Worthen, J.M., Street, I.H., Franco-Zorrilla, J.M., Zhang, W., Hill, K., Raines, T., Solano, R., Kieber, J.J., Loraine, A.E., and Schaller, G.E. (2017) Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis. Proc. Natl. Acad. Sci. USA 114:E5995-E6004.

Yamburenko, M.V., Kieber, J.J., Schaller, G.E. (2017) Dynamic patterns of expression for genes regulating cytokinin metabolism and signaling during rice inflorescence development. PLoS ONE. 12: e0176060.

Binder, B.M. and Schaller, G.E., co-editors. (2017) Ethylene Signaling: Methods and Protocols Methods Mol. Biol. Vol. 1573. Humana Press, Springer Science+Business Media LLC, New York.

Street, I.H., Mathews, D.E., Yamburenko, M.V., Sorooshzadeh, A., John, R.T., Swarup, R., Bennett, M.J., Kieber, J.J., and Schaller, G.E. (2016) Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root. Development 143:3982-3993.

Street, I.H., Aman, S., Zubo, Y., Ramzan, A., Wang, X., Shakeel, S.N., Kieber, J.J., and Schaller, G.E. (2015) Ethylene inhibits cell proliferation of the Arabidopsis root meristem. Plant Physiol. 169:338-350.

Rai, M.I., Wang, X., Thibault, D.M., Kim, H.J., Bombyk, M.M., Binder, B.M., Shakeel, S., and Schaller, G.E. (2015) The ARGOS gene family functions in a negative feedback loop to desensitize plants to ethylene. BMC Plant Biol. 15:157.

Shakeel, S.N., Gao, Z., Amir, M., Chen Y.-F., Rai, M.I., Haq, N.U., and Schaller, G.E. (2015) Ethylene regulates levels of the ethylene receptor/CTR1 signaling complex in Arabidopsis thaliana. J. Biol. Chem. 290:12415-12424

Schaller, G.E., Bishopp, A., and Kieber, J.J. (2015) The yin-yang of hormones: Cytokinin and auxin interactions in plant development. Plant Cell. 27: 44-63

Kieber, J.J. and Schaller, G.E. (2014) Cytokinins. Arabidopsis Book. 12:e0168 doi: 10.1199/tab.0168

Kim, H.J., Chiang, Y.-H., Kieber, J.J., and Schaller, G.E. (2013) SCFKMD controls cytokinin signaling by regulating the degradation of type-B response regulators. Proc. Natl. Acad. Sci. USA. 110:10028-10033.

Hill, K., Mathews, D.E., Kim, H.J., Street, I.H., Wildes, S.L., Chiang, Y.H., Mason, M.G., Alonso, J.M., Ecker, J.R., Kieber, J.J., and Schaller, G.E. (2013) Functional characterization of type-B response regulators in the Arabidopsis cytokinin response. Plant Physiol. 162:212-224.

Shakeel, S.N., Wang, X., Binder, B.M., and Schaller, G.E. (2013) Mechanisms of signal transduction by ethylene: Overlapping and non-overlapping signaling roles in a receptor family. AoB PLANTS. doi: 10.1093/aobpla/plt010

Chiang, Y.-H., Zubo, Y.O., Tapken, W., Kim, H.J., Lavanway, A.M., Howard, L., Pilon, M., Kieber, J.J., Schaller, G.E. (2012) Functional Characterization of the GATA Transcription Factors GNC and CGA1 Reveals Their Key Role in Chloroplast Development, Growth, and Division in Arabidopsis. Plant Physiol. 160: 332-348.

Hall, B.P., Shakeel, S.N., Amir, M., Haq, N.U., Qu, X. and Schaller, G.E. (2012) Histidine-kinase activity of the ethylene receptor ETR1 facilitates the ethylene response in Arabidopsis. Plant Physiol. 159:682-95

Tsai, Y.-C., Weir, N.R., Hill, K., Zhang, W., Kim, H.J., Shiu, S.-H., Schaller, G. E., Kieber, J.J. (2012) Characterization of genes involved in cytokinin signaling and metabolism from rice. Plant Physiol. 158:1666-84

Schaller, G.E., Shiu, S.H., and Armitage, J.P. (2011) Two-component systems and their co-option for eukaryotic signal transduction. Current Biology. 21:R320-R330

Mason M.G., Jha D., Salt D.E., Tester M., Hill K., Kieber J.J., Schaller G.E. (2010) Type-B response regulators ARR1 and ARR12 regulate expression of AtHKT1;1 and accumulation of sodium in Arabidopsis shoots. Plant J. 64:753-763

Chen, Y.-F., Gao, Z., Kerris III, R.J., Wang, W., Binder, B.M., Schaller, G.E. (2010) Ethylene receptors function as components of high-molecular-mass protein complexes in Arabidopsis. PLoS ONE, 5:e8640. doi:10.1371/journal.pone.0008640.

Kieber, J.J., and Schaller, G.E. (2010) The perception of cytokinin: A story 50 years in the making. Plant Physiology.154: 487-492.

Argyros, R.D., Mathews, D.E., Chiang, Y.-H., Palmer, C.M., Thibault, D.M., Etheridge, N., Argyros, D.A., Mason, M.G., Kieber, J.J., and Schaller, G.E. (2008) Type-B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development. Plant Cell 20:2102-2116

Gao, Z., Wen, C.-K., Binder, B.M.,, Chen, Y.-F., Chang, J., Chiang, Y.-H., Kerris III, R.J., Chang, C., Schaller, G.E. (2008) Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis. J. Biol. Chem. 283:23081-23810

Chen, Y.-F., Shakeel, S.N., Bowers, J., Zhao-X.-C., Etheridge, N., and Schaller, G.E. (2007) Ligand-induced degradation of the ethylene receptor ETR2 through a proteasome-dependent pathway in Arabidopsis. J. Biol. Chem. 282: 24752 – 24758

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