Lee Alan Witters

Academic Appointments
  • Eugene W. Leonard 1921 Professor of Medicine, Medical Education and Biochemistry & Cell Biology, Geisel School of Medicine at Dartmouth

  • Professor of Biological Sciences, Dartmouth College

  • Director, Teaching Science Fellows Program

Trained as a physician, an endocrinologist, and biochemist, my passion is the education of those who might travel one or more of these roads in the future. The exploration of human biology begins with the experience of being human in all its dimensions, be they physiologic, social, or cultural. Guiding students through these dimensions as a small part of their 'becoming' is my personal reward.


Life Sciences Center, Room 122
HB 6044


Biological Sciences


  • A.B. Oberlin College
  • M.D. University of Rochester School of Medicine and Dentistry

Selected Publications

  • Hurley, RL, Barre, LK, Wood, SD, Anderson, KA, Kemp, BE, Means, AR and Witters, LA (2006), Regulation of AMP-activated protein kinase by multi-site phosphorylation in response to agents that elevate cellular cAMP, J. Biol. Chem. 281, 36662-36672,

  • Barre, L, Richardson, C, Hirshman, MF, Brozinick, Fiering, S, Kemp, BE, Goodyear, LJ and Witters, LA (2007) A genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation, Am J Physiol Endo Metab, 292, E802-811

  • Gleason, CE, Lu, D, Witters, LA, Newgard, CB and Birnbaum, MJ, (2007) The role of AMPK and mTOR in nutrient sensing in pancreatic β-cells, J. Biol. Chem., 282, 10341-103451

  • Roecki, KSC, Hirshman, MF, Brandauer, J, Fujii, N.. Witters, LA and Goodyear, LJ (2007), Skeletal Muscle Adaptation to Exercise Training AMP-Activated Protein Kinase Mediates Muscle Fiber Type Shift, Diabetes, 56, 2062-2069

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