Yasmine Kamen
Postdoctoral Scholar
National MS Society Postdoctoral Fellow
I study interactions between oligodendrocyte lineage cells and neurons. During my doctoral studies, I used electrophysiology to examine how neurotransmitter signaling to oligodendrocyte precursor cells modulates their capacity to proliferate and differentiate into myelinating oligodendrocytes. As a postdoctoral fellow in the Hill lab, I use intravital imaging with genetic labels and cellular physiology sensors to study how myelinating oligodendrocytes modulate neuronal function, with a focus on understanding these processes during healthy brain plasticity and in neurological disorders like Multiple Sclerosis.
Contact
Department(s)
Biological Sciences
Education
- B.Sc. McGill University
- Ph.D. University of Cambridge
Selected Publications
Chapman TW, Kamen Y, Piedra ET, and Hill RA. Oligodendrocyte maturation alters the cell death mechanisms that cause demyelination. The Journal of Neuroscience (2024) doi: 10.1523/JNEUROSCI.1794-23.2024 PMID: 38395617
Kamen Y#, Evans KA, Sitnikov S, Spitzer SO, de Faria O Jr, Yucel M, Káradóttir RT#. Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells. Scientific Reports (2024) doi: 10.1038/s41598-024-53615-x. PMID: 38374232 #co-corresponding author
Kamen Y, Pivonkova H, Evans KA, Káradóttir RT. A Matter of State: Diversity in Oligodendrocyte Lineage Cells. The Neuroscientist (2022) doi: 10.1177/1073858420987208. PMID: 33567971
Kamen Y#, Káradóttir RT#. Combining whole-cell patch clamp and dye loading in acute brain slices with bulk RNA sequencing in embryonic to aged mice. STAR Protocols (2021) doi: 10.1016/j.xpro.2021.100439. PMID: 33899020 #co-corresponding author