Yasmine Kamen

|Research Associate
Academic Appointments

  • Postdoctoral Scholar

  • National MS Society Postdoctoral Fellow

I study interactions between oligodendrocyte lineage cells and neurons. During my doctoral studies, I used electrophysiology to examine how neurotransmitter signaling to oligodendrocyte precursor cells modulates their capacity to proliferate and differentiate into myelinating oligodendrocytes. As a postdoctoral fellow in the Hill lab, I use intravital imaging with genetic labels and cellular physiology sensors to study how myelinating oligodendrocytes modulate neuronal function, with a focus on understanding these processes during healthy brain plasticity and in neurological disorders like Multiple Sclerosis.

Contact

Yasmine.Kamen@dartmouth.edu
Life Sciences Center, Room 311
HB 6044

Department(s)

Biological Sciences

Education

  • B.Sc. McGill University
  • Ph.D. University of Cambridge

Selected Publications

  • Chapman TW, Kamen Y, Piedra ET, and Hill RA. Oligodendrocyte maturation alters the cell death mechanisms that cause demyelination. The Journal of Neuroscience (2024) doi: 10.1523/JNEUROSCI.1794-23.2024 PMID: 38395617 

  • Kamen Y#, Evans KA, Sitnikov S, Spitzer SO, de Faria O Jr, Yucel M, Káradóttir RT#. Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells. Scientific Reports (2024) doi: 10.1038/s41598-024-53615-x. PMID: 38374232  #co-corresponding author 

  • Pivoňková H*, Sitnikov S*, Kamen Y*, Vanhaesebrouck A, Matthey M, Spitzer SO, Ng YT, Tao C, de Faria O Jr, Varga BV, Káradóttir RT. Heterogeneity in oligodendrocyte precursor cell proliferation is dynamic and driven by passive bioelectrical properties. Cell Reports (2024) doi: 10.1016/j.celrep.2024.114873 PMID: 39423130   *co-first author

  • Kamen Y, Pivonkova H, Evans KA, Káradóttir RT. A Matter of State: Diversity in Oligodendrocyte Lineage Cells. The Neuroscientist (2022) doi: 10.1177/1073858420987208. PMID: 33567971 

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