Santiago Schnell

|Professor
Academic Appointments
  • Provost

  • Professor of Mathematics

  • Adjunct Professor of Biochemistry & Cell Biology

  • Adjunct Professor of Biomedical Data Science

Santiago Schnell is the Provost, Professor of Mathematics, and Adjunct Professor of Biochemistry & Cell Biology and Biomedical Data Science at Dartmouth. He previously served as the William K. Warren Foundation Dean of the College of Science at the University of Notre Dame, where he was also Professor of Biological Sciences and Applied & Computational Mathematics & Statistics.

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Contact

Parkhurst, Room 111D
HB 6004

Department(s)

Mathematics

Administration

Provost

Education

  • License in Biology, Universidad Simón Bolívar, Venezuela (Awarded: 24 Jan 1997)
  • Doctor of Philosophy (Mathematics), University of Oxford, UK (Awarded: 8 Nov 2003)

Selected Publications

  • ● S. Schnell and C. Mendoza (1997). Closed form solution for time-dependent
    enzyme kinetics. Journal of Theoretical Biology 187, 207-212.
    ● S. Schnell and T. E. Turner (2004). Reaction kinetics in intracellular
    environments with macromolecular crowding: simulations and rate laws.
    Progress in Biophysics and Molecular Biology 85, 235-260.
    ● C. I. Sandefur and S. Schnell (2011). A model of threshold behavior reveals
    rescue mechanisms of bystander proteins in conformational diseases.
    Biophysical Journal 100, 1864-1873.
    ● K. D. Walton, M. Whidden, Å. Kolterud, S. K. Shoffner, M. J. Czerwinski, J.
    Kushwaha, N. Parmar, D. Chandhrasekhar, A. M. Freddo, S. Schnell and D. L.
    Gumucio (2016). Villification in the mouse: Bmp signals control intestinal villus
    patterning. Development 143, 427-436.
    ● W. Stroberg and S. Schnell (2016). On the estimation errors of Km and V from
    time-course experiments using the Michaelis-Menten equation. Biophysical
    Chemistry
    219, 17–27.
    ● W. Stroberg, H. Atkin, Y. Savir and S. Schnell (2018). How to design an optimal
    sensor network for the unfolded protein response. Molecular Biology of the Cell
    29, 3052–3062.
    ● W. Stroberg and S. Schnell (2018) Do cellular condensates accelerate
    biochemical reactions? Lessons from microdroplet chemistry. Biophysical Journal
    115, 3-8.
    ● S. Pitchiaya, M. D.A. Mourao, A. Jalihal, L. Xiao, X. Jiang, A. M. Chinnaiyan, S.
    Schnell and N. G. Walter (2019). Dynamic recruitment of single RNAs to
    processing bodies depends on RNA functionality. Molecular Cell 74, 521-533.
    ● J. Cavataio and S. Schnell (2021). Interpreting SARS-CoV-2 fatality rate
    estimates: A case for introducing standardized reporting to improve
    communication. Mathematical Biosciences 333, 108545.
    ● S. Lauterbach, H. Dienhart, J. Range, S. Malzacher, J.-D. Spöring, D Rother, M.
    Filipa Pinto, P. Martins, C. E. Lagerman, A. S. Bommarius, A. V. Høst, J. M.
    Woodley, S. Ngubane, T. Kudanga, F. T. Bergmann, J. M. Rohwer, D. Iglezakis,
    A. Weidemann, U. Wittig, C. Kettner, N. Swainston, S. Schnell, J. Pleiss (2023).
    EnzymeML at work: seamless data flow and modelling of enzymatic data. Nature
    Methods
    20, 400–402.

    For a full and continuously updated list of publications, please visit Google Scholar.

Selected Works & Activities

● President-elect, President and Past-President, Society for Mathematical Biology,
2014-2018
● Member of the "Standards for Reporting Enzymology Data" (STRENDA)
Commission, 01/2016-present
● Editorial Board, Current Opinion in Systems Biology, 01/2016-present
● Editorial Board, Biophysical Chemistry, 10/2016-present
● Editorial Advisory Board, Biomolecular Concepts, 07/2019-present
● Editorial Board, Journal of Theoretical Biology, 02/2019-present
● Editorial Board, Scientific Data, 05/2023-present
● Editorial Advisory Board, Mathematical Biosciences, 07/2023-present