Nicholas J. Jacobs
Professor Emeritus of Microbiology and Immunology
Adjunct Professor Emeritus of Biological Sciences
Much of my research has been in the area of bacterial pathogenesis as well as clinical and public health microbiology. Special focus has been on diagnosis and antimicrobial therapy of infections in compromised hosts, such as patients with cystic fibrosis, AIDS, and cancer. Additional research areas include the biochemical and toxicological aspects of heme and chlorophyll biosynthesis in humans, bacteria, and plants.
EducationCornell University, PHD 1960
Morales DK, Grahl N, Okegbe C, Dietrich LE, Jacobs NJ, Hogan DA
Control of Candida albicans metabolism and biofilm formation by Pseudomonas aeruginosa phenazines.
MBio 2013 Jan 29; 4(1):e00526-12
Morales DK, Jacobs NJ, Rajamani S, Krishnamurthy M, Cubillos-Ruiz JR, Hogan DA
Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms.
Mol Microbiol 2010 Dec; 78(6):1379-92
Measurement of protoporphyrinogen oxidase activity. Jacobs JM, Jacobs NJ. Curr Protoc Toxicol. (2001). May;Chapter 8:Unit 8
Polyclonal Mycobacterium avium infections in patients with AIDS: variations in antimicrobial susceptibilities of different strains of M. avium isolated from the same patient. von Reyn CF, Jacobs NJ, Arbeit RD, Maslow JN, Niemczyk S. J Clin Microbiol. (1995). Apr;33(4):1008-10.